Pick your startup MVPsβ¦ ποΈ

β° Midwest Minute
Preseason is wrapping up, rosters are getting trimmed and fantasy football leagues across the Midwest are waking from hibernation. Whether youβre a strategic drafter or a vibes-only picker, it's officially Fantasy Football Draft Season. And just like the Coltsβ QB situation, your fantasy team might already be stressing you out. Roughly 13 million people in the U.S. played ESPN fantasy football last year. Oh, and the Midwest is home to two of the most fantasy-productive NFL teams: the Detroit Lions and, yes, the Kansas City Chiefs.
Speaking of the Chiefsβ¦ remember when the TODAY show predicted Taylor Swift would get engaged in 2025? As of this week, Taylor and Travis Kelce are officially engaged, just in time for kickoff. The engagement rings in KC are now as sparkly as the Super Bowl rings. Rumor has it she might even headline the halftime show this yearβready for it? Whether you're tuning in for the touchdowns or the Taylor content, one thingβs certain: the NFL season is about to take over our weekends and tailgates are about to go off. If youβre worried about spending too much time on fantasy football at workβ¦ turns out it might actually help your career.
Have any insights into the Midwest ecosystem or a funding announcement to share? Want to share your NFL fantasy team this year? Send us an email: [email protected]
π° Notable News
Featured
Exits
K5 Global acquires majority stake in Minneapolis-based HistoSonics at a $2B+ valuation
Chicago-based AbbVie to acquire Gilgamesh Pharmaceuticalsβ Bretisilocin for up to $1.2B
Chicago-based Tempus AI acquired Paige for $81.25M
Cincinnati-based 80 Acres acquired Soli Organic for an undisclosed amount
Indianapolis-based Greenlight Guru acquired Enzyme for an undisclosed amount
Startup Funding
Wugen - $115M round led by Fidelity | St. Louis
Capacity - $92M ($42.6M Series D from TVC Capital and Toloka and $50M debt from Chicago Atlantic) | St. Louis
Hemi Labs - $15M round from investors like YZi Labs, Republic Digital and HyperChain Capital | Chicago
Blue Bridge People - $5M round from angels | Cincinnati
Metaimpact - $5M round | Indianapolis
Waterly - $4M Series A led by Burnt Island Ventures | Chicago
Ostra Security - $2.6M Series A extension co-led by General Catalyst and Rally | Minneapolis
Grapefruit Health - Undisclosed Seed round | Chicago
VC Funds
O.H.I.O. Fund - $240M fund | Ohio
Portal Innovations - Raising $100M biotech fund | Chicago
Other News
Have exciting news to share? If you're announcing a funding round, exit or other milestone, send your press release to [email protected]. While we canβt share everything, we love to feature great stories from across the region.
π Mark your Calendar
Need to fill your social calendar? Weβve scoured newsletters, scanned LinkedIn and found some of the latest tech + startup events in the region. Know of any upcoming events and want to share them in our next newsletter? Send us an email: [email protected]

